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The synthesis of (15)N(7)-Hoogsteen face-labeled adenosine phosphoramidite for solid-phase RNA synthesis
ABSTRACT: We have developed an efficient route for the synthesis of (15)N(7)-labeled adenosine as phosphoramidite building block for site- and atom-specific incorporation into RNA by automated solid-phase synthesis. Such labeled RNA is required for the evaluation of selected non-canonical base pair...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225212/ https://www.ncbi.nlm.nih.gov/pubmed/28127100 http://dx.doi.org/10.1007/s00706-016-1882-8 |