Improved simplicity and practicability in copper-catalyzed alkynylation of tetrahydroisoquinoline

ABSTRACT: Alkynylation reactions of N-protected tetrahydroisoquinolines have been performed using several different protocols of cross dehydrogenative coupling. Initially, a CuCl-catalyzed method was investigated, which worked well with three different N-protecting groups, namely phenyl, PMP, and be...

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Detalles Bibliográficos
Autores principales: Gröll, Birgit, Schaaf, Patricia, Schnürch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225217/
https://www.ncbi.nlm.nih.gov/pubmed/28127095
http://dx.doi.org/10.1007/s00706-016-1877-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225217/
https://www.ncbi.nlm.nih.gov/pubmed/28127095
http://dx.doi.org/10.1007/s00706-016-1877-5

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