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Improved simplicity and practicability in copper-catalyzed alkynylation of tetrahydroisoquinoline
ABSTRACT: Alkynylation reactions of N-protected tetrahydroisoquinolines have been performed using several different protocols of cross dehydrogenative coupling. Initially, a CuCl-catalyzed method was investigated, which worked well with three different N-protecting groups, namely phenyl, PMP, and be...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225217/ https://www.ncbi.nlm.nih.gov/pubmed/28127095 http://dx.doi.org/10.1007/s00706-016-1877-5 |