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IL-1β is a key cytokine that induces trypsin upregulation in the influenza virus–cytokine–trypsin cycle
Severe influenza is characterized by a cytokine storm, and the influenza virus–cytokine–trypsin cycle is one of the important mechanisms of viral multiplication and multiple organ failure. The aim of this study was to define the key cytokine(s) responsible for trypsin upregulation. Mice were infecte...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225228/ https://www.ncbi.nlm.nih.gov/pubmed/27714503 http://dx.doi.org/10.1007/s00705-016-3093-3 |