Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion

To understand the role of glycosaminoglycans in bacterial cellular invasion, xylosyltransferase-deficient mutants of Chinese hamster ovary (CHO) cells were created using clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene targeting. When...

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Detalles Bibliográficos
Autores principales: van Wijk, Xander M., Döhrmann, Simon, Hallström, Björn M., Li, Shangzhong, Voldborg, Bjørn G., Meng, Brandon X., McKee, Karen K., van Kuppevelt, Toin H., Yurchenco, Peter D., Palsson, Bernhard O., Lewis, Nathan E., Nizet, Victor, Esko, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225314/
https://www.ncbi.nlm.nih.gov/pubmed/28074024
http://dx.doi.org/10.1128/mBio.02128-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225314/
https://www.ncbi.nlm.nih.gov/pubmed/28074024
http://dx.doi.org/10.1128/mBio.02128-16

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