Cargando…

Tissue Dimensionality Influences the Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Targets

Cytotoxic T lymphocyte (CTL)-mediated killing of virus infections and tumors occurs over a wide range of conditions. The spatial environments in which CTLs encounter target cells vary from narrow vessels, to two-dimensional epithelial tissues, to densely populated 3-dimensional (3D) T cell areas wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Gadhamsetty, Saikrishna, Marée, Athanasius F. M., de Boer, Rob J., Beltman, Joost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225319/
https://www.ncbi.nlm.nih.gov/pubmed/28123385
http://dx.doi.org/10.3389/fimmu.2016.00668