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Tissue Dimensionality Influences the Functional Response of Cytotoxic T Lymphocyte-Mediated Killing of Targets

Cytotoxic T lymphocyte (CTL)-mediated killing of virus infections and tumors occurs over a wide range of conditions. The spatial environments in which CTLs encounter target cells vary from narrow vessels, to two-dimensional epithelial tissues, to densely populated 3-dimensional (3D) T cell areas wit...

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Detalles Bibliográficos
Autores principales:	Gadhamsetty, Saikrishna, Marée, Athanasius F. M., de Boer, Rob J., Beltman, Joost B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225319/ https://www.ncbi.nlm.nih.gov/pubmed/28123385 http://dx.doi.org/10.3389/fimmu.2016.00668

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