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The role of macrophages in the susceptibility of Fc gamma receptor IIb deficient mice to Cryptococcus neoformans

Dysfunctional polymorphisms of FcγRIIb, an inhibitory receptor, are associated with Systemic Lupus Erythaematosus (SLE). Cryptococcosis is an invasive fungal infection in SLE, perhaps due to the de novo immune defect. We investigated cryptococcosis in the FcγRIIb−/− mouse-lupus-model. Mortality, aft...

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Detalles Bibliográficos
Autores principales: Surawut, Saowapha, Ondee, Thunnicha, Taratummarat, Sujittra, Palaga, Tanapat, Pisitkun, Prapaporn, Chindamporn, Ariya, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225418/
https://www.ncbi.nlm.nih.gov/pubmed/28074867
http://dx.doi.org/10.1038/srep40006