Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma

The Wnt/β-catenin signaling is abnormally activated in the progression of hepatocellular carcinoma (HCC). BCL9 is an essential co-activator in the Wnt/β-catenin signaling. Importantly, BCL9 is absent from tumors originating from normal cellular counterparts and overexpressed in many cancers includin...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Zhou, Wang, Cheng, Mo, Wang, Jing, Liu, Zhian, He, Shaohui, Luo, Xiangji, Huang, Wending, Chen, Tianrui, Yan, Wangjun, Xiao, Jianru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225427/
https://www.ncbi.nlm.nih.gov/pubmed/28074862
http://dx.doi.org/10.1038/srep40446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225427/
https://www.ncbi.nlm.nih.gov/pubmed/28074862
http://dx.doi.org/10.1038/srep40446

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