Multi-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster

Multi-cellular cluster formation of natural killer (NK) cells occurs during in vivo priming and potentiates their activation to IL-2. However, the precise mechanism underlying this synergy within NK cell clusters remains unclear. We employed lymphocyte-laden microwell technologies to modulate contac...

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Detalles Bibliográficos
Autores principales: Kim, Miju, Kim, Tae-Jin, Kim, Hye Mi, Doh, Junsang, Lee, Kyung-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225448/
https://www.ncbi.nlm.nih.gov/pubmed/28074895
http://dx.doi.org/10.1038/srep40623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225448/
https://www.ncbi.nlm.nih.gov/pubmed/28074895
http://dx.doi.org/10.1038/srep40623

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