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Multi-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster
Multi-cellular cluster formation of natural killer (NK) cells occurs during in vivo priming and potentiates their activation to IL-2. However, the precise mechanism underlying this synergy within NK cell clusters remains unclear. We employed lymphocyte-laden microwell technologies to modulate contac...
Autores principales: | Kim, Miju, Kim, Tae-Jin, Kim, Hye Mi, Doh, Junsang, Lee, Kyung-Mi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225448/ https://www.ncbi.nlm.nih.gov/pubmed/28074895 http://dx.doi.org/10.1038/srep40623 |
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