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A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins

Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variet...

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Detalles Bibliográficos
Autores principales: Kapp, Tobias G., Rechenmacher, Florian, Neubauer, Stefanie, Maltsev, Oleg V., Cavalcanti-Adam, Elisabetta A., Zarka, Revital, Reuning, Ute, Notni, Johannes, Wester, Hans-Jürgen, Mas-Moruno, Carlos, Spatz, Joachim, Geiger, Benjamin, Kessler, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225454/
https://www.ncbi.nlm.nih.gov/pubmed/28074920
http://dx.doi.org/10.1038/srep39805