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A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation. Consequently, mutations in specific integrins, or their deregulated expression, are associated with a variet...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225454/ https://www.ncbi.nlm.nih.gov/pubmed/28074920 http://dx.doi.org/10.1038/srep39805 |