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A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo
To create a new anti-tumor antibody, we conducted signal sequence trap by retrovirus-meditated expression method and identified coxsackie virus and adenovirus receptor (CXADR) as an appropriate target. We developed monoclonal antibodies against human CXADR and found that one antibody (6G10A) signifi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225458/ https://www.ncbi.nlm.nih.gov/pubmed/28074864 http://dx.doi.org/10.1038/srep40400 |