Cargando…

A novel monoclonal antibody targeting coxsackie virus and adenovirus receptor inhibits tumor growth in vivo

To create a new anti-tumor antibody, we conducted signal sequence trap by retrovirus-meditated expression method and identified coxsackie virus and adenovirus receptor (CXADR) as an appropriate target. We developed monoclonal antibodies against human CXADR and found that one antibody (6G10A) signifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kawada, Manabu, Inoue, Hiroyuki, Kajikawa, Masunori, Sugiura, Masahito, Sakamoto, Shuichi, Urano, Sakiko, Karasawa, Chigusa, Usami, Ihomi, Futakuchi, Mitsuru, Masuda, Tohru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225458/ https://www.ncbi.nlm.nih.gov/pubmed/28074864 http://dx.doi.org/10.1038/srep40400

Ejemplares similares

Generation and evaluation of a chimeric antibody against coxsackievirus and adenovirus receptor for cancer therapy
por: Sakamoto, Shuichi, et al.
Publicado: (2019)

New metastatic model of human small-cell lung cancer by orthotopic transplantation in mice
por: Sakamoto, Shuichi, et al.
Publicado: (2015)

Stromal Cells Positively and Negatively Modulate the Growth of Cancer Cells: Stimulation via the PGE2-TNFα-IL-6 Pathway and Inhibition via Secreted GAPDH-E-Cadherin Interaction
por: Kawada, Manabu, et al.
Publicado: (2015)

Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression
por: Anders, M, et al.
Publicado: (2009)

Loss of Coxsackie and adenovirus receptor downregulates α-catenin expression
por: Stecker, K, et al.
Publicado: (2009)

Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases
por: Chen, Xiong, et al.
Publicado: (2018)

Study of Coxsackie B viruses interactions with Coxsackie Adenovirus receptor and Decay-Accelerating Factor using Human CaCo-2 cell line
por: Riabi, Samira, et al.
Publicado: (2014)

Essential Role of the Coxsackie - and Adenovirus Receptor (CAR) in Development of the Lymphatic System in Mice
por: Mirza, Momina, et al.
Publicado: (2012)

Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia
por: Excoffon, Katherine J. D. A., et al.
Publicado: (2010)

Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells
por: Lenman, Annasara, et al.
Publicado: (2015)

ZEB1 limits adenoviral infectability by transcriptionally repressing the Coxsackie virus and Adenovirus Receptor
por: Lacher, Markus D, et al.
Publicado: (2011)

Coxsackie–adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
por: Hodik, M, et al.
Publicado: (2016)

Human Coxsackie- and adenovirus receptor is a putative target of neutrophil elastase-mediated shedding
por: Herrmann, Leonie, et al.
Publicado: (2022)

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1
por: Carlisle, Robert C., et al.
Publicado: (2009)

Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model
por: Hurez, Vincent, et al.
Publicado: (2002)

Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs
por: Shaw, Christian A, et al.
Publicado: (2004)

Expression of coxsackie and adenovirus receptor distinguishes transitional cancer states in therapy-induced cellular senescence
por: Wu, P C, et al.
Publicado: (2010)

Transcription Factor Sp1 Is Involved in Expressional Regulation of Coxsackie and Adenovirus Receptor in Cancer Cells
por: Chung, Sun-Ku, et al.
Publicado: (2011)

Upregulation of Coxsackie Adenovirus Receptor Sensitizes Cisplatin-Resistant Lung Cancer Cells to CRAd-Induced Inhibition
por: Sakhawat, Ali, et al.
Publicado: (2017)

ERK1/2 pathway regulates coxsackie and adenovirus receptor expression in mouse cardiac stem cells
por: Liu, Jingjin, et al.
Publicado: (2017)

Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor
por: Zhang, Yonghui, et al.
Publicado: (2020)

Loss of coxsackie and adenovirus receptor expression in human colorectal cancer: A potential impact on the efficacy of adenovirus-mediated gene therapy in Chinese Han population
por: Ma, Ying-Yu, et al.
Publicado: (2016)

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells
por: Ifie, Eseoghene, et al.
Publicado: (2018)

Marine Lectins DlFBL and HddSBL Fused with Soluble Coxsackie-Adenovirus Receptor Facilitate Adenovirus Infection in Cancer Cells BUT Have Different Effects on Cell Survival
por: Wu, Bingbing, et al.
Publicado: (2017)

Coxsackie Virus Infections in Southern Africa
por: Gear, James
Publicado: (1961)

NEUROPATHOGENICITY OF GROUP A COXSACKIE VIRUSES
por: Dalldorf, Gilbert
Publicado: (1957)

AGE AND SUSCEPTIBILITY OF MICE TO COXSACKIE A VIRUSES
por: Lerner, A. Martin, et al.
Publicado: (1962)

SUSCEPTIBILITY OF GRAVID MICE TO COXSACKIE VIRUS INFECTION
por: Dalldorf, Gilbert, et al.
Publicado: (1954)

Coxsackie encephalitis in a child in Western India
por: Shah, Ira, et al.
Publicado: (2017)

Histone Deacetylase Inhibitors Restore Cell Surface Expression of the Coxsackie Adenovirus Receptor and Enhance CMV Promoter Activity in Castration-Resistant Prostate Cancer Cells
por: Kasman, Laura, et al.
Publicado: (2012)

THE SPARING EFFECT OF COXSACKIE VIRUS INFECTION ON EXPERIMENTAL POLIOMYELITIS
por: Dalldorf, Gilbert
Publicado: (1951)

THE SURVIVAL OF POLIOMYELITIS AND COXSACKIE VIRUSES FOLLOWING THEIR INGESTION BY FLIES
por: Melnick, Joseph L., et al.
Publicado: (1952)

Coxsackie encephalitis in a child in Western India: Correspondence
por: Mandal, Anirban, et al.
Publicado: (2018)

Interferon-Induced Transmembrane Protein 1 (IFITM1) Promotes Distant Metastasis of Small Cell Lung Cancer
por: Sakamoto, Shuichi, et al.
Publicado: (2020)

IMMUNOLOGICAL REACTIONS OF THE COXSACKIE VIRUSES : II. THE COMPLEMENT FIXATION TEST
por: Kraft, Lisbeth M., et al.
Publicado: (1950)

ADAPTATION OF GROUP B COXSACKIE VIRUS TO ADULT MOUSE PANCREAS
por: Dalldorf, Gilbert, et al.
Publicado: (1952)

Hepatitis and Encephalitis due to Coxsackie Virus A9 in an Adult
por: Moreau, Brigitte, et al.
Publicado: (2011)

An Out-of-Season Case of Coxsackie B Myocarditis with Severe Rhabdomyolysis
por: Mehta, Alaap, et al.
Publicado: (2018)

Kawasaki syndrome and concurrent Coxsackie virus B3 infection
por: Rigante, Donato, et al.
Publicado: (2010)

Concurrent Coxsackie Virus A6 Infection and Kawasaki Disease
por: Matsukura, Hiro, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a0u3h0u5hfn6lvdmcqun6lha31