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Live visualization of genomic loci with BiFC-TALE

Tracking the dynamics of genomic loci is important for understanding the mechanisms of fundamental intracellular processes. However, fluorescent labeling and imaging of such loci in live cells have been challenging. One of the major reasons is the low signal-to-background ratio (SBR) of images mainl...

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Detalles Bibliográficos
Autores principales: Hu, Huan, Zhang, Hongmin, Wang, Sheng, Ding, Miao, An, Hui, Hou, Yingping, Yang, Xiaojing, Wei, Wensheng, Sun, Yujie, Tang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225478/
https://www.ncbi.nlm.nih.gov/pubmed/28074901
http://dx.doi.org/10.1038/srep40192