Insights into an evolutionary strategy leading to antibiotic resistance

Metallo-β-lactamases (MBLs) with activity towards a broad-spectrum of β-lactam antibiotics have become a major threat to public health, not least due to their ability to rapidly adapt their substrate preference. In this study, the capability of the MBL AIM-1 to evade antibiotic pressure by introduci...

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Detalles Bibliográficos
Autores principales: Hou, Chun-Feng D., Liu, Jian-wei, Collyer, Charles, Mitić, Nataša, Pedroso, Marcelo Monteiro, Schenk, Gerhard, Ollis, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225480/
https://www.ncbi.nlm.nih.gov/pubmed/28074907
http://dx.doi.org/10.1038/srep40357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225480/
https://www.ncbi.nlm.nih.gov/pubmed/28074907
http://dx.doi.org/10.1038/srep40357

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