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Insights into an evolutionary strategy leading to antibiotic resistance
Metallo-β-lactamases (MBLs) with activity towards a broad-spectrum of β-lactam antibiotics have become a major threat to public health, not least due to their ability to rapidly adapt their substrate preference. In this study, the capability of the MBL AIM-1 to evade antibiotic pressure by introduci...
Autores principales: | Hou, Chun-Feng D., Liu, Jian-wei, Collyer, Charles, Mitić, Nataša, Pedroso, Marcelo Monteiro, Schenk, Gerhard, Ollis, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225480/ https://www.ncbi.nlm.nih.gov/pubmed/28074907 http://dx.doi.org/10.1038/srep40357 |
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