Deubiquitylation of hepatitis B virus X protein (HBx) by ubiquitin-specific peptidase 15 (USP15) increases HBx stability and its transactivation activity

Hepatitis B virus X protein (HBx) plays important roles in viral replication and the development of hepatocellular carcinoma. HBx is a rapid turnover protein and ubiquitin-proteasome pathway has been suggested to influence HBx stability as treatment with proteasome inhibitors increases the levels of...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Zhi-Jun, Cao, Jia-Shou, Wu, Yan-Fang, Chen, Wan-Nan, Lin, Xinjian, Wu, Yun-Li, Lin, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225491/
https://www.ncbi.nlm.nih.gov/pubmed/28074857
http://dx.doi.org/10.1038/srep40246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225491/
https://www.ncbi.nlm.nih.gov/pubmed/28074857
http://dx.doi.org/10.1038/srep40246

Ejemplares similares