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Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer
BACKGROUND: Bone morphogenetic protein 4 (BMP4) plays an important role in cancer pathogenesis. In breast cancer, it reduces proliferation and increases migration in a cell line-dependent manner. To characterize the transcriptional mediators of these phenotypes, we performed RNA-seq and DNase-seq an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225521/ https://www.ncbi.nlm.nih.gov/pubmed/28077088 http://dx.doi.org/10.1186/s12864-016-3428-1 |