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Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer

BACKGROUND: Bone morphogenetic protein 4 (BMP4) plays an important role in cancer pathogenesis. In breast cancer, it reduces proliferation and increases migration in a cell line-dependent manner. To characterize the transcriptional mediators of these phenotypes, we performed RNA-seq and DNase-seq an...

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Detalles Bibliográficos
Autores principales:	Ampuja, M., Rantapero, T., Rodriguez-Martinez, A., Palmroth, M., Alarmo, E. L., Nykter, M., Kallioniemi, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225521/ https://www.ncbi.nlm.nih.gov/pubmed/28077088 http://dx.doi.org/10.1186/s12864-016-3428-1

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