A fission yeast cell-based system for multidrug resistant HIV-1 proteases

BACKGROUND: HIV-1 protease (PR) is an essential enzyme for viral production. Thus, PR inhibitors (PIs) are the most effective class of anti-HIV drugs. However, the main challenge to the successful use of PI drugs in patient treatment is the emergence of multidrug resistant PRs ((mdr)PRs). This study...

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Detalles Bibliográficos
Autores principales: Benko, Zsigmond, Liang, Dong, Li, Ge, Elder, Robert T., Sarkar, Anindya, Takayama, Jun, Ghosh, Arun K., Zhao, Richard Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225522/
https://www.ncbi.nlm.nih.gov/pubmed/28096973
http://dx.doi.org/10.1186/s13578-016-0131-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225522/
https://www.ncbi.nlm.nih.gov/pubmed/28096973
http://dx.doi.org/10.1186/s13578-016-0131-5

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