Cargando…
A fission yeast cell-based system for multidrug resistant HIV-1 proteases
BACKGROUND: HIV-1 protease (PR) is an essential enzyme for viral production. Thus, PR inhibitors (PIs) are the most effective class of anti-HIV drugs. However, the main challenge to the successful use of PI drugs in patient treatment is the emergence of multidrug resistant PRs ((mdr)PRs). This study...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225522/ https://www.ncbi.nlm.nih.gov/pubmed/28096973 http://dx.doi.org/10.1186/s13578-016-0131-5 |