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Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma

BACKGROUND: The DACT (Dishevelled-associated antagonist of β-catenin) family of scaffold proteins may play important roles in tumorigenesis. However, the epigenetic changes of DACT1, 2, 3 and their effect on esophageal squamous cell carcinoma (ESCC) have not been investigated so far. The aim of this...

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Detalles Bibliográficos
Autores principales: Guo, Yan-li, Shan, Bao-En, Guo, Wei, Dong, Zhi-Ming, Zhou, Zhen, Shen, Su-Peng, Guo, Xin, Liang, Jia, Kuang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225534/
https://www.ncbi.nlm.nih.gov/pubmed/28077137
http://dx.doi.org/10.1186/s12929-016-0308-6