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Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma
BACKGROUND: The DACT (Dishevelled-associated antagonist of β-catenin) family of scaffold proteins may play important roles in tumorigenesis. However, the epigenetic changes of DACT1, 2, 3 and their effect on esophageal squamous cell carcinoma (ESCC) have not been investigated so far. The aim of this...
Autores principales: | Guo, Yan-li, Shan, Bao-En, Guo, Wei, Dong, Zhi-Ming, Zhou, Zhen, Shen, Su-Peng, Guo, Xin, Liang, Jia, Kuang, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225534/ https://www.ncbi.nlm.nih.gov/pubmed/28077137 http://dx.doi.org/10.1186/s12929-016-0308-6 |
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