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Is CD47 an innate immune checkpoint for tumor evasion?

Cluster of differentiation 47 (CD47) (also known as integrin-associated protein) is a ubiquitously expressed glycoprotein of the immunoglobulin superfamily that plays a critical role in self-recognition. Various solid and hematologic cancers exploit CD47 expression in order to evade immunological er...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojuan, Kwon, Hyunwoo, Li, Zihai, Fu, Yang-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225552/
https://www.ncbi.nlm.nih.gov/pubmed/28077173
http://dx.doi.org/10.1186/s13045-016-0381-z