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T cell exhaustion: from pathophysiological basics to tumor immunotherapy
The immune system is capable of distinguishing between danger- and non-danger signals, thus inducing either an appropriate immune response against pathogens and cancer or inducing self-tolerance to avoid autoimmunity and immunopathology. One of the mechanisms that have evolved to prevent destruction...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225559/ https://www.ncbi.nlm.nih.gov/pubmed/28073373 http://dx.doi.org/10.1186/s12964-016-0160-z |