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Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain

BACKGROUND: Recent work has identified and mapped a range of posttranscriptional modifications in mRNA, including methylation of the N6 and N1 positions in adenine, pseudouridylation, and methylation of carbon 5 in cytosine (m5C). However, knowledge about the prevalence and transcriptome-wide distri...

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Detalles Bibliográficos
Autores principales: Amort, Thomas, Rieder, Dietmar, Wille, Alexandra, Khokhlova-Cubberley, Daria, Riml, Christian, Trixl, Lukas, Jia, Xi-Yu, Micura, Ronald, Lusser, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225599/
https://www.ncbi.nlm.nih.gov/pubmed/28077169
http://dx.doi.org/10.1186/s13059-016-1139-1