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Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

BACKGROUND: The causative role of the pro-inflammatory cytokine IL-6 in prostate cancer progression has been well established at molecular level. However, whether and how IL-6 may play a role in prostate cancer risk and development is not well defined. One limitation factor to acquiring this knowled...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Zhang, Jinyu, Frey, Lewis, Gang, Xiao, Wu, Kongming, Liu, Qian, Lilly, Michael, Wu, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225646/
https://www.ncbi.nlm.nih.gov/pubmed/28077171
http://dx.doi.org/10.1186/s13045-016-0386-7