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Threonine(175), a novel pathological phosphorylation site on tau protein linked to multiple tauopathies
Microtubule associated protein tau (tau) deposition is associated with a spectrum of neurodegenerative diseases collectively termed tauopathies. We have previously shown that amyotrophic lateral sclerosis (ALS) with cognitive impairment (ALSci) is associated with tau phosphorylation at Thr(175) and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225652/ https://www.ncbi.nlm.nih.gov/pubmed/28077166 http://dx.doi.org/10.1186/s40478-016-0406-4 |