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Advances and challenges in logical modeling of cell cycle regulation: perspective for multi-scale, integrative yeast cell models

The eukaryotic cell cycle is robustly designed, with interacting molecules organized within a definite topology that ensures temporal precision of its phase transitions. Its underlying dynamics are regulated by molecular switches, for which remarkable insights have been provided by genetic and molec...

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Detalles Bibliográficos
Autores principales: Barberis, Matteo, Todd, Robert G., van der Zee, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225787/
https://www.ncbi.nlm.nih.gov/pubmed/27993914
http://dx.doi.org/10.1093/femsyr/fow103