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Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach

Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both...

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Autores principales: Gündüz, Özgür, Emeksiz, Mehmet Can, Atasoy, Pinar, Kidir, Mehtap, Yalçin, Selim, Demirkan, Serkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225968/
https://www.ncbi.nlm.nih.gov/pubmed/28326183
http://dx.doi.org/10.4081/dr.2016.6819
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author Gündüz, Özgür
Emeksiz, Mehmet Can
Atasoy, Pinar
Kidir, Mehtap
Yalçin, Selim
Demirkan, Serkan
author_facet Gündüz, Özgür
Emeksiz, Mehmet Can
Atasoy, Pinar
Kidir, Mehtap
Yalçin, Selim
Demirkan, Serkan
author_sort Gündüz, Özgür
collection PubMed
description Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient’s head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed.
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spelling pubmed-52259682017-03-21 Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach Gündüz, Özgür Emeksiz, Mehmet Can Atasoy, Pinar Kidir, Mehtap Yalçin, Selim Demirkan, Serkan Dermatol Reports Case Report Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient’s head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed. PAGEPress Publications, Pavia, Italy 2017-01-04 /pmc/articles/PMC5225968/ /pubmed/28326183 http://dx.doi.org/10.4081/dr.2016.6819 Text en ©Copyright Ö. Gündüz et al. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gündüz, Özgür
Emeksiz, Mehmet Can
Atasoy, Pinar
Kidir, Mehtap
Yalçin, Selim
Demirkan, Serkan
Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
title Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
title_full Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
title_fullStr Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
title_full_unstemmed Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
title_short Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
title_sort signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225968/
https://www.ncbi.nlm.nih.gov/pubmed/28326183
http://dx.doi.org/10.4081/dr.2016.6819
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