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Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach
Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225968/ https://www.ncbi.nlm.nih.gov/pubmed/28326183 http://dx.doi.org/10.4081/dr.2016.6819 |
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author | Gündüz, Özgür Emeksiz, Mehmet Can Atasoy, Pinar Kidir, Mehtap Yalçin, Selim Demirkan, Serkan |
author_facet | Gündüz, Özgür Emeksiz, Mehmet Can Atasoy, Pinar Kidir, Mehtap Yalçin, Selim Demirkan, Serkan |
author_sort | Gündüz, Özgür |
collection | PubMed |
description | Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient’s head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed. |
format | Online Article Text |
id | pubmed-5225968 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-52259682017-03-21 Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach Gündüz, Özgür Emeksiz, Mehmet Can Atasoy, Pinar Kidir, Mehtap Yalçin, Selim Demirkan, Serkan Dermatol Reports Case Report Up to 10% of patients with visceral malignancies develop skin metastases during their clinical course and these metastases constitute about 2% of all skin cancers. Skin metastasis may be the first sign of a clinically silent visceral cancer or represent recurrence of an internal malignancy. In both situations, they are associated with poor prognosis, which can partly be attributed to underdiagnosis. In this paper, a case of relapsing gastric adenocarcinoma, which manifested itself as asymptomatic cutaneous papules and nodules on a patient’s head and neck, is reported and histopathological approach to the cutaneous lesions containing signet-ring cell is briefly reviewed. PAGEPress Publications, Pavia, Italy 2017-01-04 /pmc/articles/PMC5225968/ /pubmed/28326183 http://dx.doi.org/10.4081/dr.2016.6819 Text en ©Copyright Ö. Gündüz et al. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Gündüz, Özgür Emeksiz, Mehmet Can Atasoy, Pinar Kidir, Mehtap Yalçin, Selim Demirkan, Serkan Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach |
title | Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach |
title_full | Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach |
title_fullStr | Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach |
title_full_unstemmed | Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach |
title_short | Signet-ring Cells in the Skin: A Case of Late-onset Cutaneous Metastasis of Gastric Carcinoma and a Brief Review of Histological Approach |
title_sort | signet-ring cells in the skin: a case of late-onset cutaneous metastasis of gastric carcinoma and a brief review of histological approach |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225968/ https://www.ncbi.nlm.nih.gov/pubmed/28326183 http://dx.doi.org/10.4081/dr.2016.6819 |
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