Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

PURPOSE: Corneal neovascularization and scarring commonly lead to significant vision loss. This study was designed to determine whether a small-molecule inhibitor of galectin-3 can inhibit both corneal angiogenesis and fibrosis in experimental mouse models. METHODS: Animal models of silver nitrate c...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen*, Wei-Sheng, Cao, Zhiyi, Leffler, Hakon, Nilsson, Ulf J., Panjwani, Noorjahan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225999/
https://www.ncbi.nlm.nih.gov/pubmed/28055102
http://dx.doi.org/10.1167/iovs.16-20009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225999/
https://www.ncbi.nlm.nih.gov/pubmed/28055102
http://dx.doi.org/10.1167/iovs.16-20009

Ejemplares similares