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Room temperature structure of human IgG4-Fc from crystals analysed in situ

The Fc region of IgG antibodies (Cγ2 and Cγ3 domains) is responsible for effector functions such as antibody-dependent cell-mediated cytotoxicity and phagocytosis, through engagement with Fcγ receptors, although the ability to elicit these functions differs between the four human IgG subclasses. A k...

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Detalles Bibliográficos
Autores principales: Davies, Anna M., Rispens, Theo, Ooijevaar-de Heer, Pleuni, Aalberse, Rob C., Sutton, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226057/
https://www.ncbi.nlm.nih.gov/pubmed/27915153
http://dx.doi.org/10.1016/j.molimm.2016.11.021