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Pharmacology of Modulators of Alternative Splicing

More than 95% of genes in the human genome are alternatively spliced to form multiple transcripts, often encoding proteins with differing or opposing function. The control of alternative splicing is now being elucidated, and with this comes the opportunity to develop modulators of alternative splici...

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Detalles Bibliográficos
Autores principales: Bates, David O., Morris, Jonathan C., Oltean, Sebastian, Donaldson, Lucy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226212/
https://www.ncbi.nlm.nih.gov/pubmed/28034912
http://dx.doi.org/10.1124/pr.115.011239