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Contribution of Sigma‐1 receptor to cytoprotective effect of afobazole

Anxiolytic afobazole (5‐Ethoxy‐2‐[2‐(morpholino)‐ethylthio]benzimidazole dihidrochloride) has pronounced ligand properties toward Sigma‐1 receptor (σ1 receptor,SigmaR1) and MT (3) receptors. Our previous work demonstrated that afobazole possess cytoprotective effect in the in vitro model of menadion...

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Detalles Bibliográficos
Autores principales: Voronin, Mikhail V., Kadnikov, Ilya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226281/
https://www.ncbi.nlm.nih.gov/pubmed/28097006
http://dx.doi.org/10.1002/prp2.273