A selective GPR40 (FFAR1) agonist LY2881835 provides immediate and durable glucose control in rodent models of type 2 diabetes

LY2881835 is a selective, potent, and efficacious GPR40 agonist. The objective of the studies described here was to examine the pharmacological properties of LY2881835 in preclinical models of T2D. Significant increases in insulin secretion were detected when LY2881835 was tested in primary islets f...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yanyun, Song, Min, Riley, Jonathan P., Hu, Charlie C., Peng, Xianbu, Scheuner, Donalyn, Bokvist, Krister, Maiti, Pranab, Kahl, Steven D., Montrose‐Rafizadeh, Chahrzad, Hamdouchi, Chafiq, Miller, Anne Reifel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226292/
https://www.ncbi.nlm.nih.gov/pubmed/28097011
http://dx.doi.org/10.1002/prp2.278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226292/
https://www.ncbi.nlm.nih.gov/pubmed/28097011
http://dx.doi.org/10.1002/prp2.278

Ejemplares similares