Cargando…

Metformin Induces Growth Inhibition and Cell Cycle Arrest by Upregulating MicroRNA34a in Renal Cancer Cells

BACKGROUND: Metformin is a widely used biguanide drug for the treatment of type 2 diabetes. It has been revaluated as a potential anti-cancer drug with promising activity in various tumors. However, the precise mechanisms underlying the suppression of cancer cells by metformin remain not well unders...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Wei, Wang, Lei, Sheng, Halei, Qiu, Jing, Zhang, Di, Zhang, Le, Yang, Fan, Tang, Dahai, Zhang, Kebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226302/
https://www.ncbi.nlm.nih.gov/pubmed/28045889
http://dx.doi.org/10.12659/MSM.898710