Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription

Dysregulation of RNA polymerase I (Pol I)-dependent ribosomal DNA (rDNA) transcription is a consistent feature of malignant transformation that can be targeted to treat cancer. Understanding how rDNA transcription is coupled to the availability of growth factors and nutrients will provide insight in...

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Detalles Bibliográficos
Autores principales: Kang, Jian, Kusnadi, Eric P., Ogden, Allison J., Hicks, Rodney J., Bammert, Lukas, Kutay, Ulrike, Hung, Sandy, Sanij, Elaine, Hannan, Ross D., Hannan, Katherine M., Pearson, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226478/
https://www.ncbi.nlm.nih.gov/pubmed/27385002
http://dx.doi.org/10.18632/oncotarget.10346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226478/
https://www.ncbi.nlm.nih.gov/pubmed/27385002
http://dx.doi.org/10.18632/oncotarget.10346

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