Cargando…

Saikosaponin a inhibits LPS-induced inflammatory response by inducing liver X receptor alpha activation in primary mouse macrophages

The aim of this study was to investigate the effects of SSa on LPS-induced endotoxemia in mice and clarify the possible mechanism. An LPS-induced endotoxemia mouse model was used to confirm the anti-inflammatory activity of SSa in vivo. The primary mouse macrophages were used to investigate the mole...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Zhengkai, Wang, Jingjing, Shi, Mingyu, Liu, Weijian, Yang, Zhengtao, Fu, Yunhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226486/
https://www.ncbi.nlm.nih.gov/pubmed/27285988
http://dx.doi.org/10.18632/oncotarget.9863