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Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo

The development of resistance to platinum drugs in cancer cells severely reduces the efficacy of these drugs. Thus, the discovery of novel drugs or combined strategies to overcome drug resistance is imperative. In addition to our previous finding that combined D-penicillamine with platinum drugs exe...

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Detalles Bibliográficos
Autores principales: Chen, Szu-Jung, Kuo, Ching-Chuan, Pan, Hsin-Yi, Tsou, Tsui-Chun, Yeh, Szu-Ching, Chang, Jang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226510/
https://www.ncbi.nlm.nih.gov/pubmed/27384479
http://dx.doi.org/10.18632/oncotarget.10336