ß-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation

Mutations in ß-catenin are traditionally described as late events in thyroid cancer progression. However, the functional implications of ß-catenin dysregulation in the context of tumor initiating events remain unclear. The aim of this work was to investigate whether the two main oncogenic drivers in...

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Detalles Bibliográficos
Autores principales: Sastre-Perona, Ana, Riesco-Eizaguirre, Garcilaso, Zaballos, Miguel A., Santisteban, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226519/
https://www.ncbi.nlm.nih.gov/pubmed/27384483
http://dx.doi.org/10.18632/oncotarget.10356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226519/
https://www.ncbi.nlm.nih.gov/pubmed/27384483
http://dx.doi.org/10.18632/oncotarget.10356

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