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ß-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation
Mutations in ß-catenin are traditionally described as late events in thyroid cancer progression. However, the functional implications of ß-catenin dysregulation in the context of tumor initiating events remain unclear. The aim of this work was to investigate whether the two main oncogenic drivers in...
Autores principales: | Sastre-Perona, Ana, Riesco-Eizaguirre, Garcilaso, Zaballos, Miguel A., Santisteban, Pilar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226519/ https://www.ncbi.nlm.nih.gov/pubmed/27384483 http://dx.doi.org/10.18632/oncotarget.10356 |
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