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Disruption of the EZH2/miRNA/β-catenin signaling suppresses aerobic glycolysis in glioma

EZH2 is up-regulated in various cancer types, implicating its role in tumorigenesis. Our recent data have shown that repression of EZH2 inhibited glioma growth by inhibition β-catenin signaling. Here, we identified several miRNAs that were repressed by EZH2, which in turn regulate β-catenin expressi...

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Detalles Bibliográficos
Autores principales: Wang, Yingyi, Wang, Min, Wei, Wenjin, Han, Dongfeng, Chen, Xincheng, Hu, Qi, Yu, Tianfu, Liu, Ning, You, Yongping, Zhang, Junxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226520/
https://www.ncbi.nlm.nih.gov/pubmed/27385092
http://dx.doi.org/10.18632/oncotarget.10370