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High CRLF2 expression associates with IKZF1 dysfunction in adult acute lymphoblastic leukemia without CRLF2 rearrangement

Overexpression of cytokine receptor-like factor 2 (CRLF2) due to chromosomal rearrangement has been observed in acute lymphoblastic leukemia (ALL) and reported to contribute to oncogenesis and unfavorable outcome in ALL. We studied B-ALL and T-ALL patients without CRLF2 rearrangement and observed th...

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Detalles Bibliográficos
Autores principales: Ge, Zheng, Gu, Yan, Zhao, Gang, Li, Jianyong, Chen, Baoan, Han, Qi, Guo, Xing, Liu, Juan, Li, Hui, Yu, Michael D., Olson, Justin, Steffens, Sadie, Payne, Kimberly J., Song, Chunhua, Dovat, Sinisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226542/
https://www.ncbi.nlm.nih.gov/pubmed/27391346
http://dx.doi.org/10.18632/oncotarget.10437