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Novel ERα positive breast cancer model with estrogen independent growth in the bone microenvironment

Despite successful therapeutic options for estrogen receptor-α (ERα)+ breast cancer, resistance to endocrine therapy frequently occurs leading to tumor recurrence. In addition to intrinsic changes in the cancer cells, herein we demonstrate that tumor cell-microenvironment interactions can drive recu...

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Detalles Bibliográficos
Autores principales: Capietto, Aude-Hélène, Chan, Szeman Ruby, Ricci, Biancamaria, Allen, Julie A., Su, Xinming, Novack, Deborah V, Schreiber, Robert D., Faccio, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226545/
https://www.ncbi.nlm.nih.gov/pubmed/27391074
http://dx.doi.org/10.18632/oncotarget.10443