Cargando…

Novel ERα positive breast cancer model with estrogen independent growth in the bone microenvironment

Despite successful therapeutic options for estrogen receptor-α (ERα)+ breast cancer, resistance to endocrine therapy frequently occurs leading to tumor recurrence. In addition to intrinsic changes in the cancer cells, herein we demonstrate that tumor cell-microenvironment interactions can drive recu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Capietto, Aude-Hélène, Chan, Szeman Ruby, Ricci, Biancamaria, Allen, Julie A., Su, Xinming, Novack, Deborah V, Schreiber, Robert D., Faccio, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226545/ https://www.ncbi.nlm.nih.gov/pubmed/27391074 http://dx.doi.org/10.18632/oncotarget.10443

Ejemplares similares

Down-regulation of PLCγ2–β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer
por: Capietto, Aude-Hélène, et al.
Publicado: (2013)

Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer
por: D’Amico, Lucia, et al.
Publicado: (2016)

Peroxynitrite promotes immune evasion by reducing tumor antigenicity
por: Capietto, Aude-Hélène, et al.
Publicado: (2022)

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
por: Ruhland, Megan K., et al.
Publicado: (2016)

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas
por: Chan, Szeman Ruby, et al.
Publicado: (2012)

Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner
por: Favre, Julie, et al.
Publicado: (2021)

Cancer neoantigens and immunogenicity: mutation position matters
por: Capietto, Aude-Hélène, et al.
Publicado: (2020)

Sources of Cancer Neoantigens beyond Single-Nucleotide Variants
por: Capietto, Aude-Hélène, et al.
Publicado: (2022)

Endogenous and Therapeutic Estrogens: Maestro Conductors of the Microenvironment of ER+ Breast Cancers
por: Schuler, Linda A., et al.
Publicado: (2021)

Estrogens Attenuate Oxidative Stress and the Differentiation and Apoptosis of Osteoblasts by DNA-Binding-Independent Actions of the ERα
por: Almeida, Maria, et al.
Publicado: (2010)

Estrogen Signaling in ERα-Negative Breast Cancer: ERβ and GPER
por: Girgert, Rainer, et al.
Publicado: (2019)

Human estrogen receptor-α (ER-α) transactivation by selective estrogen receptor modulators (SERMs) on VIT regulatory region in ER-α-negative breast cancer cell line Evsa-T transiently transfected by ER-α
por: Nyamagana Butera, IP, et al.
Publicado: (2001)

Estrogen/ER in anti-tumor immunity regulation to tumor cell and tumor microenvironment
por: Wang, Tiecheng, et al.
Publicado: (2021)

The Co-Expression of Estrogen Receptors ERα, ERβ, and GPER in Endometrial Cancer
por: Hojnik, Marko, et al.
Publicado: (2023)

Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens
por: Gong, Ping, et al.
Publicado: (2014)

Functions and physiological roles of two types of estrogen receptors, ERα and ERβ, identified by estrogen receptor knockout mouse
por: Lee, Hye-Rim, et al.
Publicado: (2012)

A role for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) in collagen biosynthesis in mouse skin
por: Markiewicz, Margaret, et al.
Publicado: (2012)

Estrogenic microenvironment generated by organochlorine residues in adipose mammary tissue modulates biomarker expression in ERα-positive breast carcinomas
por: Muñoz-de-Toro, Mónica, et al.
Publicado: (2006)

Pancreatic Insulin Content Regulation by the Estrogen Receptor ERα
por: Alonso-Magdalena, Paloma, et al.
Publicado: (2008)

Classical Estrogen Receptors and ERα Splice Variants in the Mouse
por: Irsik, Debra L., et al.
Publicado: (2013)

Xenoestrogens Alter Estrogen Receptor (ER) α Intracellular Levels
por: La Rosa, Piergiorgio, et al.
Publicado: (2014)

ERα expression in T lymphocytes is dispensable for estrogenic effects in bone
por: Gustafsson, K L, et al.
Publicado: (2018)

Respective role of membrane and nuclear estrogen receptor (ER) α in the mandible of growing mice: Implications for ERα modulation
por: Vinel, Alexia, et al.
Publicado: (2018)

Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer
por: Li, Yuanyuan, et al.
Publicado: (2013)

Estrogen-induced SDF-1α production promotes the progression of ER-negative breast cancer via the accumulation of MDSCs in the tumor microenvironment
por: Ouyang, Liquan, et al.
Publicado: (2016)

Prevention of Obesity and Insulin Resistance by Estrogens Requires ERα Activation Function-2 (ERαAF-2), Whereas ERαAF-1 Is Dispensable
por: Handgraaf, Sandra, et al.
Publicado: (2013)

Amplification of WHSC1L1 regulates expression and estrogen‐independent activation of ERα in SUM‐44 breast cancer cells and is associated with ERα over‐expression in breast cancer
por: Irish, Jonathan C., et al.
Publicado: (2016)

Correction: Xenoestrogens Alter Estrogen Receptor (ER) α Intracellular Levels
Publicado: (2014)

HER2 and ERβ2 downregulate estrogen-responsive element-mediated transcription activity of ERα-positive cells in response to estrogen stimulation
por: Park, B-W, et al.
Publicado: (2005)

Distribution and Prognostic Significance of Estrogen Receptor α (ERα), Estrogen Receptor β (ERβ), and Human Epidermal Growth Factor Receptor 2 (HER-2) in Thyroid Carcinoma
por: Mishra, Anjali, et al.
Publicado: (2020)

Estrogen receptor alpha (ERα) mRNA copy numbers in immunohistochemically ERα-positive-, and negative breast cancer tissues
por: Poola, Indira, et al.
Publicado: (2007)

Estrogen Receptor (ER)-α36 Is Involved in Estrogen- and Tamoxifen-Induced Neuroprotective Effects in Ischemic Stroke Models
por: Zou, Wei, et al.
Publicado: (2015)

Forskolin Stimulates Estrogen Receptor (ER) α Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms
por: Tsai, Houng-Wei, et al.
Publicado: (2022)

Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics
por: Ricci, Biancamaria, et al.
Publicado: (2020)

Estradiol Regulates Expression of Estrogen Receptor ERα46 in Human Macrophages
por: Murphy, Amy J., et al.
Publicado: (2009)

Regulation of ERα Stability and Estrogen Signaling in Breast Cancer by HOIL-1
por: Ding, Jianing, et al.
Publicado: (2021)

Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
por: Vydra, Natalia, et al.
Publicado: (2021)

Cognitive Functions, Concentration of Endogenous Estradiol, Estrogen Receptor α (ERα) Polymorphism in Postmenopausal Women
por: Bojar, Iwona, et al.
Publicado: (2016)

Bisphenol AF Is a Full Agonist for the Estrogen Receptor ERα but a Highly Specific Antagonist for ERβ
por: Matsushima, Ayami, et al.
Publicado: (2010)

Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by β3 integrin
por: Faccio, Roberta, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_ehug7qirh2cqu956did5tg528l