Histone deacetylase inhibitors regulate P-gp expression in colorectal cancer via transcriptional activation and mRNA stabilization

Histone deacetylase inhibitors (HDACIs) are emerging as a novel class of anti-tumor drugs. But the effect of HDACIs in tumors treatment has been disappointing, which mainly due to the acquisition of resistance to HDACIs. However, the underlying mechanisms have not been clearly understood. In this st...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Huang, Cheng, Zhao, Liang, Zhang, Huan, Yang, Jing Mo, Luo, Peng, Zhan, Bing-Xiang, Pan, Qing, Li, Jun, Wang, Bao-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226552/
https://www.ncbi.nlm.nih.gov/pubmed/27409663
http://dx.doi.org/10.18632/oncotarget.10488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226552/
https://www.ncbi.nlm.nih.gov/pubmed/27409663
http://dx.doi.org/10.18632/oncotarget.10488

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