Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis

We previously demonstrated that cell-surface gC1qR is a key regulator of lamellipodia formation and cancer metastasis. Here, we screened a monoclonal mouse antibody against gC1qR to prevent cell migration by neutralizing cell-surface gC1qR. The anti-gC1qR antibody prevented growth factor-stimulated...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Beom-Chan, Hwang, Hyun-Jung, An, Hyoung-Tae, Lee, Hyun, Park, Jun-Sub, Hong, Jin, Ko, Jesang, Kim, Chungho, Lee, Jae-Seon, Ko, Young-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226562/
https://www.ncbi.nlm.nih.gov/pubmed/27363031
http://dx.doi.org/10.18632/oncotarget.10267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226562/
https://www.ncbi.nlm.nih.gov/pubmed/27363031
http://dx.doi.org/10.18632/oncotarget.10267

Ejemplares similares