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Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis

We previously demonstrated that cell-surface gC1qR is a key regulator of lamellipodia formation and cancer metastasis. Here, we screened a monoclonal mouse antibody against gC1qR to prevent cell migration by neutralizing cell-surface gC1qR. The anti-gC1qR antibody prevented growth factor-stimulated...

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Detalles Bibliográficos
Autores principales:	Kim, Beom-Chan, Hwang, Hyun-Jung, An, Hyoung-Tae, Lee, Hyun, Park, Jun-Sub, Hong, Jin, Ko, Jesang, Kim, Chungho, Lee, Jae-Seon, Ko, Young-Gyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226562/ https://www.ncbi.nlm.nih.gov/pubmed/27363031 http://dx.doi.org/10.18632/oncotarget.10267

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