Sirtuin 3 enhanced drug sensitivity of human hepatoma cells through glutathione S-transferase pi 1/JNK signaling pathway

SIRT3, a class III histone deacetylase, has been implicated in various cancers as a novel therapeutic target. In hepatocellular carcinoma (HCC), we previously reported that SIRT3 induced cell apoptosis by regulating GSK-3β/Bax signaling pathway. Downregulation of SIRT3 in HCC cells facilitates tumor...

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Detalles Bibliográficos
Autores principales: Tao, Na-Na, Zhou, Hong-Zhong, Tang, Hua, Cai, Xue-Fei, Zhang, Wen-Lu, Ren, Ji-Hua, Zhou, Li, Chen, Xiang, Chen, Ke, Li, Wan-Yu, Liu, Bo, Yang, Qiu-Xia, Cheng, Sheng-Tao, Huang, Li-Xia, Huang, Ai-Long, Chen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226572/
https://www.ncbi.nlm.nih.gov/pubmed/27367026
http://dx.doi.org/10.18632/oncotarget.10319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226572/
https://www.ncbi.nlm.nih.gov/pubmed/27367026
http://dx.doi.org/10.18632/oncotarget.10319

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